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Figure 2: Cartoon showing steps involved in the making of gal-single-knockout pigs. The galactocyltransferase gene has been eliminated on one allele by cloning. Breeding of such pigs will result in gal-double-knockout pigs with the gene being eliminated on both alleles. The tissues of such animals do not express the gal-epitope (Courtesy of Revivicor Inc, Blacksburg, Virginia, USA) |
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