Indian Journal of Urology
ORIGINAL ARTICLE
Year
: 2013  |  Volume : 29  |  Issue : 2  |  Page : 110--113

Paratesticular rhabdomyosarcoma in young adults: A tertiary care institute experience


Ritesh Kumar1, Rakesh Kapoor1, Divya Khosla1, Narendra Kumar1, Sushmita Ghoshal1, Arup Kumar Mandal2, Bishan Das Radotra3, Suresh Chander Sharma1 
1 Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Urology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Ritesh Kumar
Department of Radiotherapy and Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh
India

Introduction: Paratesticular rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. It represents only 7% of all patients entered in the Intergroup Rhabdomyosarcoma Study (IRS) and 17% of all malignant intrascrotal tumors in children less than 15 years old. We present our experience in combined modality management of 10 successive patients of paratesticular RMS. Material and Methods: We retrospectively reviewed 10 patients of paratesticular RMS treated in our institute from July 2004 to December 2010. Clinical characteristics and treatment modality in form of surgery and chemotherapy (CCT) were noted. Statistical analysis was done with regards to progression-free survival (PFS) and overall survival (OS) using Kaplan-Meier survival analysis. Results: The median age of the patients was 16.5 years. The median duration of symptoms was 5 months. Five patients had retroperitoneal lymphadenopathy (RPLAP) while three had lung metastases and one had orbital metastases. All patients underwent high inguinal orchidectomy followed by systemic chemotherapy (CCT). Retroperitoneal node dissection was not a required staging procedure. Four patients had partial response to treatment while six had complete response. Mean duration of PFS was 48 months and mean OS was 56 months. Conclusions: Paratesticular RMS are rare neoplasms with aggressive growth patterns. Cure rates have dramatically improved and 60% of patients in our series had complete response. This success is due to development of multimodality and risk adapted treatment approaches.


How to cite this article:
Kumar R, Kapoor R, Khosla D, Kumar N, Ghoshal S, Mandal AK, Radotra BD, Sharma SC. Paratesticular rhabdomyosarcoma in young adults: A tertiary care institute experience.Indian J Urol 2013;29:110-113


How to cite this URL:
Kumar R, Kapoor R, Khosla D, Kumar N, Ghoshal S, Mandal AK, Radotra BD, Sharma SC. Paratesticular rhabdomyosarcoma in young adults: A tertiary care institute experience. Indian J Urol [serial online] 2013 [cited 2021 Apr 11 ];29:110-113
Available from: https://www.indianjurol.com/article.asp?issn=0970-1591;year=2013;volume=29;issue=2;spage=110;epage=113;aulast=Kumar;type=0