Year : 2009 | Volume
: 25 | Issue : 2 | Page : 161--168
Opportunistic infections (noncytomegalovirus) in live related renal transplant recipients
PB Vinod, Raj Kumar Sharma
Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India
The purpose of review was increasing number of opportunistic infections with use of newer immunosuppression and difficulty in diagnosis and management of such patients. For this review, MEDLINE database was searched from 2000 to 2006 with the keywords of opportunistic infections in renal transplantation.
Opportunistic infection is a serious clinical complication in patients receiving immunosuppressive therapy after kidney transplantation. The two major factors for successful renal transplantation are better control of rejection and better prevention and treatment of infection. In renal allograft recipient, immunosuppressive drug therapy is the major cause of immunocompromised status and occurrence of infections, which arise most commonly as a result of invasion by endogenous opportunists. The opportunistic infections with varicella zoster viruses, parvovirus B-19, polyomavirus, nocardia and mucormycosis in immunosuppressed patients were present with severe complications that are reviewed in this article. As a result of use of strong immunosuppressive drugs like tacrolimus, mycophenolate mofetyl (MMF) and antirejection therapy with antithymocyte globulins (ATG), these infections are now seen frequently, so they should always be included in differential diagnostic consideration. New diagnostic procedures and new treatment strategies are required to allow early detection and successful treatment of opportunistic infections in kidney transplant recipients.
Raj Kumar Sharma
Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow-226 014, UP
|How to cite this article:|
Vinod P B, Sharma RK. Opportunistic infections (noncytomegalovirus) in live related renal transplant recipients.Indian J Urol 2009;25:161-168
|How to cite this URL:|
Vinod P B, Sharma RK. Opportunistic infections (noncytomegalovirus) in live related renal transplant recipients. Indian J Urol [serial online] 2009 [cited 2022 Oct 5 ];25:161-168
Available from: https://www.indianjurol.com/article.asp?issn=0970-1591;year=2009;volume=25;issue=2;spage=161;epage=168;aulast=Vinod;type=0