Year : 2007 | Volume
: 23 | Issue : 3 | Page : 305--310
The potential advantages of transplanting organs from pig to man: A transplant Surgeon«SQ»s view
Carl G Groth
Karolinska Institute, Stockholm, Sweden
Once pig organs can be transplanted into humans, transplantation will move into a new era. There will be unlimited access to undamaged organs and cells for transplantation and, eventually, donation from deceased or live human beings will become obsolete. Furthermore, it will be possible to alleviate graft rejection, at least in part, by genetic modification of the source animal. Currently, there are three major obstacles to performing transplantations from pig to man: 1) a powerful immune barrier, 2) a potential risk of transmitting microorganisms, particularly endogenous retrovirus and 3) ethical issues related to the future recipients and to society at large.
This article will first discuss ongoing work with regards to overcoming the current obstacles. Then, the many potential advantages of using pig organs will be listed. Next, the criteria for selecting the first patients for transplantation with pig organs, will be briefly discussed. Finally, some promising observations made in the context of early attempts at transplanting porcine cells to patients, will be mentioned.
Carl G Groth
Karolinska Institute, Stockholm
|How to cite this article:|
Groth CG. The potential advantages of transplanting organs from pig to man: A transplant Surgeon's view.Indian J Urol 2007;23:305-310
|How to cite this URL:|
Groth CG. The potential advantages of transplanting organs from pig to man: A transplant Surgeon's view. Indian J Urol [serial online] 2007 [cited 2020 Nov 26 ];23:305-310
Available from: https://www.indianjurol.com/article.asp?issn=0970-1591;year=2007;volume=23;issue=3;spage=305;epage=310;aulast=Groth;type=0