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Year : 2022  |  Volume : 38  |  Issue : 4  |  Page : 307-308

Development of phimosis as an adverse drug reaction to capecitabine with irinotecan

1 Consultant Urologist, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat, India
2 Department of Paediatrics, M K Shah Medical College, Ahmedabad, Gujarat, India

Correspondence Address:
Priyeshkumar Patel
Consultant Urologist, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/iju.iju_169_22

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We present a case of a 32-year-old male who developed capecitabine-induced phimosis which resolved spontaneously without the need for circumcision within a few days of discontinuation of chemotherapy. The patient was on capecitabine with irinotecan chemotherapy for peritoneal metastasis from adenocarcinoma of the lower esophagus. A detailed literature review showed a few case reports with penile and scrotal erythema, ulceration, and swelling along with hand-foot syndrome, but none reported the occurrence of phimosis with spontaneous resolution.

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