| CASE REPORT |
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| Year : 2022 | Volume
: 38
| Issue : 4 | Page : 307-308 |
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Development of phimosis as an adverse drug reaction to capecitabine with irinotecan
Priyeshkumar Patel1, Nagendra Nath Mishra1, Taral Patel2
1 Consultant Urologist, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat, India
2 Department of Paediatrics, M K Shah Medical College, Ahmedabad, Gujarat, India
Correspondence Address:
Priyeshkumar Patel
Consultant Urologist, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/iju.iju_169_22
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We present a case of a 32-year-old male who developed capecitabine-induced phimosis which resolved spontaneously without the need for circumcision within a few days of discontinuation of chemotherapy. The patient was on capecitabine with irinotecan chemotherapy for peritoneal metastasis from adenocarcinoma of the lower esophagus. A detailed literature review showed a few case reports with penile and scrotal erythema, ulceration, and swelling along with hand-foot syndrome, but none reported the occurrence of phimosis with spontaneous resolution.
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