|Year : 2020 | Volume
| Issue : 1 | Page : 4-5
Department of Urology, All India Institute of Medical Sciences, New Delhi, India
|Date of Web Publication||2-Jan-2020|
Department of Urology, All India Institute of Medical Sciences, New Delhi
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Kumar R. What's inside. Indian J Urol 2020;36:4-5
| Groin Management in Penile Cancer|| |
Penile cancer is relatively common in India. Despite the obvious appearance, patients often present late with inguinal metastasis. However, a significant proportion have no palpable nodes, and understanding the management of these patients is important to offer them the best chances of a cure. Niyogi et al. review the indication of groin dissection in patients with clinically negative groins, an area of some debate and uncertainty.
| Robotic Partial Nephrectomy|| |
Robot-assisted surgery is now widely available, including India, and while Bora et al. present the SWOT analysis on this technology, Gul et al. review the techniques and outcomes of robot-assisted partial nephrectomy, one of the most common indications for robotic assistance. This surgery has undergone a number of modifications built upon the experience gained from laparoscopic surgery. Some of the issues discussed include the assistant sparing technique, usage of sliding clip for renorrhaphy, and warm ischemia preventing methods. The authors also review the outcomes of this surgery in terms of oncology and functional results.
| Open Surgery for Pheochromocytoma|| |
Pheochromocytomas continue to be considered a difficult surgery both because of the hemodynamic and anesthetic challenges and also the rarity of the condition. Prakash et al. present their experience of open surgery in 25 patients out of a cohort of 106 patients. The summary of their findings is that the most common reasons for performing open surgery include tumor those requiring concomitant procedures. However, they also show that the outcomes in such surgeries are no worse than other patients.
| Holmium Laser for Ureterocele|| |
The holmium:yttrium-aluminum-garnet laser has proven to be one of the most versatile of energy sources in the urological operating rooms with its excellent soft-tissue and stone fragmentation abilities. It has been used to replace the diathermy as an energy source in a number of surgeries. The ability to deliver energy through a slim fiber adds to its versatility for pediatric patients, and Di Renzo et al. present data on its use in decompression of ureteroceles in pediatric patients. They summarize that the laser is a safe and effective option and may even have some advantages over electrocautery.
| Urinary Markers of Bladder Cancer|| |
Patients with nonmuscle invasive bladder cancer require long-term follow-up with invasive cystoscopy at regular intervals. Biomarkers, particularly those that can be measured in urine, have been a target of research in an effort to decrease the need for such intensive follow-up. Kapoor et al. present their data on one such marker, minichromosome maintenance protein 2 – a cell cycle regulatory protein, in 150 patients compared with 100 controls and suggest that this may be a sensitive and specific marker that deserves further investigation.
| Eras Protocol for Robot Assisted Cystectomy|| |
The ERAS protocol is widely used in surgical units, either in its entirety or in some modified form, to decrease postoperative complications and hospital stay. Radical cystectomy with urinary diversion is possibly the most morbid of procedures performed by urological surgeons, and all attempts to minimize its complications are likely to be useful. Tamhankar et al. describe the use of the ERAS protocol in a cohort of patients undergoing robot-assisted radical cystectomy with intracorporeal ileal conduit urinary diversion in 35 patients and report their outcomes. The incidence of complications continues to be high at 45% including 14% major complications. The authors suggest that more data from multi-institutional studies would be required to assess the true value of the intervention.
| Ischemia-Reperfusion Injury during Kidney Transplant|| |
Despite the high technical success rate of renal transplantation, particularly in live-related donors, ischemia-reperfusion injury is a potential source of delayed or decreased function. Animal models have been used to assess the role of stem cells in preventing this injury. Osman et al. describe an extensive canine study using both bone marrow-derived mesenchymal stem cells and adipose tissue-derived mesenchymal stem cells and suggest that such interventions may reduce the incidence of ischemic reperfusion injury.
| Urinary Biomarkers in Prostate Cancer|| |
Continuing on the theme of minimally invasive biomarker estimation for the detection of urological cancers, Shrivastava et al. report a study evaluating urinary prostate-specific antigen and microseminoprotein-beta in men with prostate cancer. They note that in men with cancer, the levels of these markers remain constant despite a prostatic massage while the levels rise in men who do not have cancer. They hypothesize that this may be related to architectural change in glands in prostate cancer and these markers may help identify a cohort of men with indication for prostate biopsy.
| Indian Journal of Urologyawards 2019|| |
A journal survives on its readership and a scientific journal, additionally, on its authors and reviewers. This first issue of the year carries the list of awardees of the best papers and best reviewers of the journal for 2019.
Financial support and sponsorship:
Conflicts of interest:
There are no conflicts of interest.
| References|| |
Niyogi D, Noronha J, Pal M, Bakshi G, Prakash G. Management of clinically node negative groin in patients with penile cancer. Indian J Urol 2020;36:8-15. [Full text]
Bora GS, Narain TA, Sharma AP, Mavuduru RS, Devana SK, Singh SK, et al
. Robot assisted surgery in India: SWOT analysis. Indian J Urol 2019;36:1-3.
Gul ZG, Tam A, Badani KK. Robotic partial nephrectomy: The current status. Indian J Urol 2020;36:16-20. [Full text]
Prakash P, Ramachandran R, Tandon N, Kumar R. Open surgery for pheochromocytoma: Current indications and outcomes from a retrospective cohort. Indian J Urol 2020;36:21-5. [Full text]
Di Renzo D, Pizzuti G, Lauriti G, Cascini V, Lelli Chiesa P. Holmium: Yttrium aluminum garnet laser for endoscopic decompression of ureterocele in the first months of life: A comparison with electrosurgery. Indian J Urol 2020;36:26-31.
Kapoor K, Datta C, Pal DK. Immunocytochemical detection of minichromosome maintenance protein 2 as a potential urinary based marker of bladder cancer: A prospective observational study. Indian J Urol 2020;36:32-6. [Full text]
Tamhankar AS, Ahluwalia P, Patil SR, Nambiath S, Gautam G. Implementation of ERAS protocol in robot-assisted radical cystectomy with intracorporeal ileal conduit urinary diversion: An outcome analysis beyond the learning curve. Indian J Urol 2020;36:37-43. [Full text]
Osman Y, Hamed SM, Barakat NM, Khater S, Gabr M, Mosbah A, et al
. Prophylaxis against renal ischemia reperfusion injury in canine model: Stem cell approach. Indian J Urol 2020;36:44-9. [Full text]
Shrivastava P, Garg H, Bhat M, Dinda A, Kumar R. Urinary prostate? Specific antigen and microseminoprotein? Beta levels in men with and without prostate cancer: A prospective cohort study. Indian J Urol 2020;36:50-5.