|Year : 2017 | Volume
| Issue : 4 | Page : 259-260
Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India
|Date of Web Publication||27-Sep-2017|
Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Goel A. What's inside. Indian J Urol 2017;33:259-60
| Towards Non-Invasive Method to Predict Recurrence in Non-Muscle-Invasive Bladder Cancer|| |
One of the major limitations of minimal-invasive treatment for nonmuscle invasive bladder cancer (NMIBC) is the need for regular cystoscopies to look for recurrence. Cystoscopies are painful, invasive, and expensive. Many centers do not have flexible endoscopes with the result that this procedure is performed using rigid endoscopes (often under local anesthesia). This is an important reason why patients may not follow-up in spite of understanding the importance of cystoscopies. Mandhani et al. have reported their limited experience with the use of micro-RNA-21 as a potential maker that can predict bladder tumor recurrence in NMIBC. In their series of 31 patients, they found that miR-21 was upregulated (>4-fold, P = 0.003), and phosphatase and tensin homolog levels were significantly lower (<7-fold, P = 0.001) in tumor tissue relative to normal bladders. Moreover, the fold change in miR-21 levels was significantly higher (>3-fold, P = 0.03) in patients showing recurrence compared to those in which tumor did not recur. Further, Kaplan–Meier analysis showed that overexpression of miR-21 corresponds to less time to recurrence with higher cumulative hazard. This may help identify patients who do not need regular cystoscopies.
| Robotic Retroperitoneal Lymphadenectomy for Postchemotherapy Residual Mass in Testicular Tumors Patients|| |
Retroperitoneal lymph node dissection is recommended for residual masses after chemotherapy for nonseminomatous germ cell tumors since germ cell tumor elements may persist in about 50% of patients. Singh and co-workers report their experience with robotic retroperitoneal lymphadenectomy in a series of 13 such men. They report a median yield of 20 lymph nodes. Three patients had positive lymph nodes with teratoma germ cell tumor on histology. Ten patients had only necrosis in lymph nodes. After median follow-up 23 months, no systemic or retroperitoneal recurrence was found. Four patients developed chyle leak. One patient was managed conservatively with diet modification, one with intranodal lipiodol lymphangiography and two patients were managed surgically. The authors conclude that robotic lymphadenectomy is safe and feasible for postchemotherapy residual mass with accepted complication rate.
| Standard, Tubeless or Totally Tubeless Percutaneous Nephrolithotomy? Answer from a Randomized Controlled Study|| |
There has been a running debate about the optimum exit policy after percutaneous nephrolithotomy (PCNL). With increasing confidence in this procedure, many surgeons now avoid leaving behind tubes in the patient's body. With 25 patients in each group, the authors found that tubeless and totally tubeless procedures were safe. Moreover, totally tubeless PCNL significantly reduced postoperative pain and morbidity compared to the tubeless method.
| What Is the Best Method to Measure Ejaculatory Latency in Indian Men?|| |
A stopwatch is considered the standard method to measure intravaginal ejaculatory latency time (IELT) for the definition of premature ejaculation (PE). In a study involving 42 couples with PE, Bhat and Shastry sought to assess the reliability of the stopwatch method in Indian couples. They reported that the use of a stopwatch was not accurate in Indian patients. Instead, the self-assessed IELT correlated more accurately with symptoms of PE.
| Defining Predictors of Success of Endoscopic Sclerotherapy for Chyluria|| |
Endoscopic sclerotherapy is a standard treatment option in patients suffering from chyluria. Endoscopic sclerotherapy using a variety of agents have been described. The response to these agents has been variable. The cause of this variability is ill-defined. In a fairly large study involving 157 patients Purkait et al. reported that the factors predicting recurrence were higher clinical grade, higher number of pretreatment courses, and high urinary TG and cholesterol.
| Is There a Role of Fetuin-A in Causing Urolithiasis?|| |
In a case–control study the authors have tried to answer the controversy if low fetuin-A levels were responsible for urolithiasis. While evaluating 41 individuals in both groups, the authors found that patients with urolithiasis have lower urine fetuin-A and creatinine-adjusted serum fetuin-A levels.
| Role of Follow-Up Urodynamic Study in Patients of Neurogenic Bladder|| |
In this comprehensive review, the author discusses the role of follow-up urodynamics as defined by various societies for different indications. He has discussed the impact of follow-up urodynamics on patient management. Follow-up urodynamics help assess the efficacy of treatment, the need for additional therapy and identification of patients who need closer follow-up.
| Experience with Treatment of Tubularized Urethral Plate Urethroplasty in Children with Megameatus Intact Prepuce|| |
Mega-meatus intact prepuce (MIP) is an uncommon anatomical variant of hypospadias. Bhat et al. report their experience of tubularized urethral plate urethroplasty (TUPU) in mega MIP. From their database of 1026 patients with hypospadias, the authors identified 13 cases of megameatus variant of hypospadias. They report excellent cosmetic and functional results with TUPU technique.
| Simplifying Calyceal Access during Percutaneous Nephrolithotomy with Use of Minimal Access Guide|| |
With the aim to improve puncture efficacy, decrease puncture time, reduce fluoroscopy time, reduce instability of puncture needle and improve learning curve during PCNL using Bull's eye technique, investigators from All India Institute of Medical Sciences, Bhubaneshwar describe a novel device. In a comparative study, involving 60 patients, this cheap device was shown to be better.
| References|| |
Mitash N, Agnihotri S, Tiwari S, Agrawal V, Mandhani A. MicroRNA-21 could be a molecular marker to predict the recurrence of nonmuscle invasive bladder cancer. Indian J Urol 2017;33:283-90. [Full text]
Singh A, Chatterjee S, Bansal P, Bansal A, Rawal S. Robot-assisted retroperitoneal lymph node dissection: Feasibility and outcome in postchemotherapy residual mass in testicular cancer. Indian J Urol 2017;33:304-9. [Full text]
Bhat S, Lal J, Paul F. A randomized controlled study comparing the standard, tubeless, and totally tubeless percutaneous nephrolithotomy procedures for renal stones from a tertiary care hospital. Indian J Urol 2017;33:310-4. [Full text]
Bhat GS, Shastry A. Use of a stopwatch to measure ejaculatory latency may not be accurate among Indian patients. Indian J Urol 2017;33:300-3. [Full text]
Purkait B, Goel A, Garg Y, Pant S, Pal Singh BP, Sankhwar SN. Are there any factors affecting the outcome of endoscopic sclerotherapy in filarial chyluria? A prospective study. Indian J Urol 2017;33:294-9. [Full text]
Arora R, Abrol N, Antonisamy B, Vanitha S, Chandrasingh J, Kumar S, et al
. Urine and serum fetuin-A levels in patients with urolithiasis. Indian J Urol 2017;33:291-3. [Full text]
Sinha S. Follow-up urodynamics in patients with neurogenic bladder. Indian J Urol 2017;33:267-75. [Full text]
Bhat A, Bhat M, Bhat A, Singh V. Results of tubularized urethral plate urethroplasty in Megameatus Intact Prepuce. Indian J Urol 2017;33:315-8. [Full text]
Chowdhury PS, Nayak P, David D, Mallick S. Mini access guide to simplify calyceal access during percutaneous nephrolithotomy: A novel device. Indian J Urol 2017;33:319-22. [Full text]