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Year : 2010  |  Volume : 26  |  Issue : 2  |  Page : 193-195

Does rejection have a role in lymphocele formation post renal transplantation? A single centre experience

Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India

Correspondence Address:
Mahesh Desai
Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat - 387 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-1591.65385

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Aim : To assess the relation of acute rejection with respect to lymphocele incidence and determine the effect of lymphocele with graft survival. Methods : The paper is a singlecenter retrospective data review of renal transplant recipients from 1980 to 2007. A total of 1700 patients received kidneys from live donation, and 9 patients received from cadaver donor. The standard transplant technique was performed in all. Lymphocele incidence, demography, relation to rejection episodes, type of immunosuppression, and management options were studied. Univariate analysis was performed to assess the role of rejection to lymphocele formation. Results : 47 (35 males and 12 females) patients had symptomatic lymphocele in the post-transplant period. 51% of the lymphocele patients had history of rejection as compared to overall rejection rate of 20% (P = 0.009). 4 (7.2%) had at least 1 rejection and 19 (40.4%) had more than one rejection episodes. All 47 patients required aspiration. Of the 14 patients who did not settle with a maximum of two aspirations underwent marsupilization (5 open and 9 laparoscopic). 1, 5, and 10 year graft survival of overall transplant recipient and post-transplant lymphocele patients was 86.54%, 82.41% and 76.36% vs. 86.44%, 81.2% and 68.14%, respectively. Conclusion : Acute rejection episodes were associated with statistically increased risk of lymphocele. There was no adverse outcome of graft with lymphocele formation after rejection episodes with respect to the overall graft survival.

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