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CASE REPORT |
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| Year : 2002 | Volume
: 19
| Issue : 1 | Page : 87-88 |
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Eosinophilic cystitis masquerading as a bladder tumor - a case report
P Jacob John, P Ranka, KD Shukla
Department of Urology, Institute of Kidney Diseases and Research Centre & Institute of Transplantation Sciences, Ahmedabad, India
Correspondence Address:
P Jacob John
Department of Urology, Institute of Kidney Diseases & Research Centre & Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad - 380 016
India
 Source of Support: None, Conflict of Interest: None  | Check |
Keywords: Eosinophilic Cystitis Bladder
How to cite this article:
John P J, Ranka P, Shukla K D. Eosinophilic cystitis masquerading as a bladder tumor - a case report. Indian J Urol 2002;19:87-8 |
 Case Report | |  |
A 42-year-old male presented with hematuria and irritative bladder symptoms of 6 months' duration. His serum reports were normal and urine analysis showed haematuria. Cytology was negative for malignant cells. Ultrasound scan showed a hypoechoic bladder mass with thickened bladder wall and normal upper tracts. CT scan [Figure - 1] confirmed the 6.6 x 8.1 x 5 cm 3 bladder tumor on the anterior and lateral walls of the bladder. He was subjected for transurethral resection of the bladder tumor and the histopathology [Figure - 2] revealed dense infiltration of all bladder layers with eosinophils diagnostic of eosinophilic cystitis. His follow up ultrasound 5 months showed no recurrence and patient is asymptomatic.
| Comments | | |
The initial description of eosinophilic cystitis dates back to 1960 when it was described by Brown and Palubinskas. [1] Though case reports appear infrequently Van den Ouden performed a pooled analysis of 135 cases from the literature. [2] The age of presentation ranges from second to eighth decade. There is a slight male predilection for this disease, the ratio being 1.3:1. The definite cause of this disease is not clear. However it is known to be associated with transitional cell carcinoma, patients receiving intravesical chemotherapy, respiratory diseases, various drugs like tranilast, cyclophosphamide. 3 Peripheral eosinophilia is noted in some patients with some of them even showing eosinophils in urine. The renal function is preserved except in some cases where there is upper tract dilatation due to eosinophilic infiltration and later fibrosis in the bladder and ureter. It can be confused clinically and cystoscopically with invasive bladder cancer. Treatment primarily consists of transurethral resection of tumor combined with antihistamines and steroids in some cases.[3]
| References | | |
| 1. | Palubinskas AJ. Eosinophilic cystitis : case report of eosinophilic infiltration of the urinary bladder. Radiology 1960; 75: 589.  [PUBMED] |
| 2. | Van den Ouden D. Diagnosis and management of eosinophilic cystitis : A pooled analysis of 135 cases. Eur Urol 2000; 37(4): 386. |
| 3. | Reza S, Malek. Eosinophilic cystitis in adults. J Urol 2001: 165: 805. |
[Figure - 1], [Figure - 2]
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