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Year : 2002  |  Volume : 19  |  Issue : 1  |  Page : 87-88

Eosinophilic cystitis masquerading as a bladder tumor - a case report

Department of Urology, Institute of Kidney Diseases and Research Centre & Institute of Transplantation Sciences, Ahmedabad, India

Correspondence Address:
P Jacob John
Department of Urology, Institute of Kidney Diseases & Research Centre & Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad - 380 016
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Source of Support: None, Conflict of Interest: None

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Keywords: Eosinophilic Cystitis Bladder

How to cite this article:
John P J, Ranka P, Shukla K D. Eosinophilic cystitis masquerading as a bladder tumor - a case report. Indian J Urol 2002;19:87-8

How to cite this URL:
John P J, Ranka P, Shukla K D. Eosinophilic cystitis masquerading as a bladder tumor - a case report. Indian J Urol [serial online] 2002 [cited 2023 Feb 3];19:87-8. Available from:

   Case Report Top

A 42-year-old male presented with hematuria and irri­tative bladder symptoms of 6 months' duration. His se­rum reports were normal and urine analysis showed haematuria. Cytology was negative for malignant cells. Ultrasound scan showed a hypoechoic bladder mass with thickened bladder wall and normal upper tracts. CT scan [Figure - 1] confirmed the 6.6 x 8.1 x 5 cm 3 bladder tumor on the anterior and lateral walls of the bladder. He was sub­jected for transurethral resection of the bladder tumor and the histopathology [Figure - 2] revealed dense infiltration of all bladder layers with eosinophils diagnostic of eosi­nophilic cystitis. His follow up ultrasound 5 months showed no recurrence and patient is asymptomatic.

   Comments Top

The initial description of eosinophilic cystitis dates back to 1960 when it was described by Brown and Palubinskas. [1] Though case reports appear infrequently Van den Ouden performed a pooled analysis of 135 cases from the litera­ture. [2] The age of presentation ranges from second to eighth decade. There is a slight male predilection for this dis­ease, the ratio being 1.3:1. The definite cause of this dis­ease is not clear. However it is known to be associated with transitional cell carcinoma, patients receiving intra­vesical chemotherapy, respiratory diseases, various drugs like tranilast, cyclophosphamide. 3 Peripheral eosinophilia is noted in some patients with some of them even show­ing eosinophils in urine. The renal function is preserved except in some cases where there is upper tract dilatation due to eosinophilic infiltration and later fibrosis in the blad­der and ureter. It can be confused clinically and cysto­scopically with invasive bladder cancer. Treatment primarily consists of transurethral resection of tumor com­bined with antihistamines and steroids in some cases.[3]

   References Top

1.Palubinskas AJ. Eosinophilic cystitis : case report of eosinophilic infiltration of the urinary bladder. Radiology 1960; 75: 589.  Back to cited text no. 1  [PUBMED]  
2.Van den Ouden D. Diagnosis and management of eosinophilic cystitis : A pooled analysis of 135 cases. Eur Urol 2000; 37(4): 386.   Back to cited text no. 2    
3.Reza S, Malek. Eosinophilic cystitis in adults. J Urol 2001: 165: 805.  Back to cited text no. 3    


  [Figure - 1], [Figure - 2]


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