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Year : 2002  |  Volume : 18  |  Issue : 2  |  Page : 160-163

Primary adenocarcinoma of renal pelvis & ureter: Report of three cases

Department of Surgery, Pathology & Radiology, North Bengal Medical College & Hospital, Darjeeling, India

Correspondence Address:
Anup Kumar Kundu
4, P.C. Sarkar Sarani, Hakimpara, Siliguri (W.B.) - 734 401
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3 rare cases of primary adenocarcinoma of renal pelvis and ureter are illustrated here.

Keywords: Renal Pelvic Tumour; Adenocarcinoma; Ure-teric SOL; Haematuria

How to cite this article:
Kundu AK, Giri A, Kaviraj SP. Primary adenocarcinoma of renal pelvis & ureter: Report of three cases. Indian J Urol 2002;18:160-3

How to cite this URL:
Kundu AK, Giri A, Kaviraj SP. Primary adenocarcinoma of renal pelvis & ureter: Report of three cases. Indian J Urol [serial online] 2002 [cited 2023 Mar 20];18:160-3. Available from:

   Introduction Top

Primary adenocarcinoma of renal pelvis and ureter is an extremely rare tumour, representing less than 1 % of all renal tumours. [1],[2] Magumi et al [3] reported 92 nd case of pri­mary adenocarcinoma of the renal pelvis. Most of the cases are reported from Japan. [3],[4],[5],[6] We had encountered 3 such cases which are described here.

   Results Top

All the patients in our series had good postoperative re­covery except the male diabetic one who had burst abdo­men and was managed accordingly. Histopathology of all the cases showed adenocarcinoma of renal pelvis and ure­ter. All of them are in regular follow-up for last 38 months without any recurrence.

   Discussion Top

The majority of the tumours in the renal pelvis and ure­ter (uro-epithelial tumours) are transitional cell carcino­mas (TCC). Less common are squamous cell carcinomas (metaplastic, about 10%) and rarest are primary adeno­carcinomas. [7] The rare primary adenocarcinoma of the re­nal pelvis and ureter is usually associated with calculi, long-term urinary obstruction and inflammation. [8],[9] These tumours are subdivided into i) tubulovillous, ii) mucinous, and iii) papillary non-intestinal categories. The first two groups representing intestinal adenocarcinoma constitute 93% of cases. [8] The mucinous adenocarcinoma have a bet­ter prognosis and occur in elder patients, but the papillary non-intestinal variety occurs in younger individuals and is not necessarily associated with infection. Most of the tumours are solitary. either in renal pelvis or in the ureter. But Lauritzen et al [10] observed multifocal tumours of both renal pelvis & ureter, in 4 out of 37 cases of their series. We have also the same experience.

The radiological investigations to be done are : ultra­sonography (USG). intravenous (IVU) and retrograde urography, CT and if needed Doppler study. IVU shows the functional status of the affected kidney and combined with retrograde urography, usually shows a filling defect in the renal pelvis and ureter alongwith hydronephrosis and hydroureter (due to obstruction). USG shows a iso or hypoechoic soft tissue (solid) SOL at the renal pelvis ex­tending into the upper end of ureter with or without hydro­nephrotic changes. CT is the investigation of choice and demonstrates the tumour with a total evaluation, e.g., appear­ance, extent, local spread and its effect on renal function. The final diagnosis is certainly by post-operative biopsy.

The treatment of these tumours is radical nephrectomy and total ureterectomy including the intravesical part. The prognosis depends on the grade and stage of the tumours. Again Lauritzen et al [10] state that adenocarcinoma and sq­uamous cell carcinoma were high grade and late stage tu­mours in their series which is not in our case. Radio and chemotherapy had little role to play in these tumours. The initial diagnosis by ureteroscopy and brush biopsy may be helpful.

   References Top

1.Srinivas V. Renal tumour. In : Srinivas V (ed.). Urological oncol­ogy. Munnbai. India Printing House 1997: 2-19.  Back to cited text no. 1    
2.Nepal Lec.unberri S. Pascual Piedrola JI, Arrondo Arrondo JL, Ipiens Azner A. Primary ureteral adenocarcinoma. ureteroscopic diagnosis. Arch Esp Urol 1992; 45: 29-31.  Back to cited text no. 2    
3.Megumi Y. Ohniori K. Nishimura K. Primary adenocarcinoma of the renal pelvis in young male: a case report. Acta Urol lap 1998; 44: 817-820.  Back to cited text no. 3    
4.Kim YI, Yoon DH. Lee SW et al. Multicentric papillary adenocar­cinoma of the renal pelvis and ureter: Report of a case with ul­trastructure study. Cancer 1998; 62: 2402.  Back to cited text no. 4    
5.Sakamoto N. Naito S, Kotoh S et al. Recurrence following surgery for primary renal pelvic and ureteric cancer - clinico pathologic analysis of distant metastasis. Jap J Urol 1992: 83: 658-663.  Back to cited text no. 5    
6.Kobayashi S. Ohniori M, Akaeda T. Ohmori H. Miyaji Y. Primary adenocarcinoma of renal pelvis : Report of two cases and brief re­view of literature. Acta Pathol Jap 1983: 33: 589-597.  Back to cited text no. 6    
7.Judith AW Webb. The renal collecting system: Uroepithelial tu­mours. In : Miere H. Cosgrove D. Dewbury K. Fart - ant P (eds.). Clinical ultrasound : Abdominal & General ultrasound. London. Churchill Livingstone 2001; 579.  Back to cited text no. 7    
8.Stein A. Sova Y. Lurie M et al. Adenocarcinoma of the renal pelvis: report of two cases, one with simultaneous transitional cell carci­noma of bladder. Urol hit 1988; 43: 299.  Back to cited text no. 8    
9.Spires SE, Banks ER. Cibull ML et al. Adenocarcinoma of renal pelvis. Arch Path Lab Med 1993; 117: 1156-1160.  Back to cited text no. 9    
10.Lauritzen AF. Kvist E. Bredisen J. Luke M. Primary carcinoma of the upper urinary tract. Acta Pathol Microbiol Scand 1987: 95: 7­10.  Back to cited text no. 10    


  [Figure - 1], [Figure - 2], [Figure - 3], [Figure - 4]

  [Table - 1]

This article has been cited by
1 Cytodiagnosis of mucinous cystadenocarcinoma of renal pelvis - A rare case report
Bharathi, K. and Anuradha, S. and Khalique, A.
International Journal of Pharma and Bio Sciences. 2012; 3(4): 136-141
2 Mucinous adenocarcinoma of the renal pelvis with adenocarcinoma in situ of the ureter
Raphael, V. and Sailo, S. and Bhuyan, A. and Phukan, M.
Urology Annals. 2011; 3(3): 164-166


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