| CASE REPORT |
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| Year : 2001 | Volume
: 17
| Issue : 2 | Page : 170-172 |
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Intrarenal neuroblastoma - a diagnostic dilemma: A report of three cases
Anupam Lall, Minu Bajpai, Devendra Kumar Gupta
Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Devendra Kumar Gupta
Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi - 110 029
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Differentiation between the Wilms' tumor (WT) and the intrarenal neuroblastoma (IRNB) is imperative, as the prognosis and the treatment are different for these conditions. It may pose a diagnostic challenge to distinguish them pre-operatively. Over the period of last 10 years (1990-1999), 3 children aged 2 months to 4 years were diagnosed to have IRNB. 2 cases were operated with a provisional diagnosis of WT, but on histology were found to have neuroblastoma. Taking benefit from our previous experience, the third case we encountered with a renal lump and bony metastasis with clinical features not consistent with the diagnosis of Wilms' tumor was further investigated. Urinary catecholamines were significantly elevated and there was bone marrow involvement and positive bone scan for multiple bony metastasis. 2 patients are on chemotherapy and follow-up for last 6 months, while 1 died 6 years back after a follow-up of 2 years. Patients who have a renal mass on imaging, with clinical features of rapid deterioration in general condition and evidence of bony secondaries, should undergo work-up for neuroblastoma pre-operatively to confirm the diagnosis. |
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