| ORIGINAL ARTICLE |
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| Year : 2001 | Volume
: 17
| Issue : 2 | Page : 141-144 |
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Outcome of children with posterior urethral valves: Prognostic factors
RA Kukreja, RM Desai, RB Sabnis, SH Patel, MR Desai
Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India
Correspondence Address:
M R Desai
Department of Urology, Muljibhai Patel Urological Hospital, Dr. Virendra Desai Road, Nadiad - 387 001, Gujarat
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Posterior urethral valves present with a wide spectrum of renal and bladder pathology. These changes may persist despite successful treatment of the primary obstruction, leading to a gradual progress towards renal insf ciency. This study reviews retrospectively a series of 70 children with posterior urethral valves who presented at our institute over the last 10 years, with an aim to identify the prognostic factors and help in defining the end result and implicating the correct treatment protocol. These included age at presentation and intervention (less than or more than 2 years), recurrent urosepsis, presence of vesico-ureteric reflux, renal parenchymal damage as seen on ultrasound, vesical dysfunction and the nadir serum creatinine level. 29% of children had renal insufficiency at the end of 3-years' follow-up. Factors important in the progression towards renal insufficiency were evaluated. Factors found to be statistically significant with a p value <0.05 were age at intervention more than 2 years, recurrent urosepsis, bilateral high grade vesico-ureteric reflex, bilateral parenchymal damage as seen on ultrasonography and nadir serum creatinine of more than 0.8 mg%. |
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