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ORIGINAL ARTICLE
Year : 2001  |  Volume : 17  |  Issue : 2  |  Page : 141-144

Outcome of children with posterior urethral valves: Prognostic factors


Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, India

Correspondence Address:
M R Desai
Department of Urology, Muljibhai Patel Urological Hospital, Dr. Virendra Desai Road, Nadiad - 387 001, Gujarat
India
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Source of Support: None, Conflict of Interest: None


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Posterior urethral valves present with a wide spectrum of renal and bladder pathology. These changes may per­sist despite successful treatment of the primary obstruc­tion, leading to a gradual progress towards renal insf ciency. This study reviews retrospectively a series of 70 children with posterior urethral valves who pre­sented at our institute over the last 10 years, with an aim to identify the prognostic factors and help in defining the end result and implicating the correct treatment proto­col. These included age at presentation and intervention (less than or more than 2 years), recurrent urosepsis, pres­ence of vesico-ureteric reflux, renal parenchymal dam­age as seen on ultrasound, vesical dysfunction and the nadir serum creatinine level. 29% of children had renal insufficiency at the end of 3-years' follow-up. Factors important in the progression towards renal insufficiency were evaluated. Factors found to be statistically signifi­cant with a p value <0.05 were age at intervention more than 2 years, recurrent urosepsis, bilateral high grade vesico-ureteric reflex, bilateral parenchymal damage as seen on ultrasonography and nadir serum creatinine of more than 0.8 mg%.


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