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Year : 1987  |  Volume : 4  |  Issue : 1  |  Page : 20-22

Comparative study of surgical complications in genito-urinary tuberculosis treated with conventional and modern chemotherapeutic regimes.

Department of Urology, Kasturba Medical College Hospital, Manipal

Correspondence Address:
V Sreenivas
Department of Urology, Kasturba Medical College Hospital, Manipal

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Source of Support: None, Conflict of Interest: None

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A retrospective analysis of 54 patients of proved genito-urinary tuberculosis, treated between the period 1978 to 1983, was carried out to determine the treatment response. Eighteen patients out of 54 received the conventional drugs consisting of streptomycin, isoniazid and paraamino salycylic acid, whereas the remaining 36, who presented after 1980, were given the modern chemotherapeutic drugs-namely rifampicin, isoniazid and pyrazinamide. The incidence of surgical complications was 16.6 percent in the former group and 30.5 percent in the latter. The effective control of the disease process with modern drugs appears to be associated with rapidly progressive scarring and severe tissue destruction. This necessitates the need for close supervision starting at the initiation of drug treatment and monthly followup (at least in the initial 6 months) to enable early detection of complications and surgical intervention if indicated to conserve the renal function.

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